European Journal of Pediatrics

, Volume 156, Issue 6, pp 463–464

The Marshall-Smith syndrome: a review of the laryngeal complications

  • A. Cullen
  • T. A. Clarke
  • T. P. O'Dwyer
MEDICAL GENETICS

DOI: 10.1007/s004310050640

Cite this article as:
Cullen, A., Clarke, T. & O'Dwyer, T. Eur J Pediatr (1997) 156: 463. doi:10.1007/s004310050640

Abstract

The Marshall-Smith syndrome is characterised by a triad of facial dysmorphism, failure to thrive and accelerated osseous maturation. We report a further case of this rare syndrome with the unusual but previously reported complication of laryngeal hypoplasia and review the associated laryngeal anomalies that have been reported to date.

Conclusion Severe airway obstruction due to congenital anomalies must be excluded in any dysmorphic child presenting with respiratory distress at birth. Rapid airway assessment will enable early and appropriate intervention and may be important when deciding on the long-term plan for the infant.

Key words Marshall-Smith syndrome   Accelerated osseus maturation  Laryngeal anomalies

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • A. Cullen
    • 2
  • T. A. Clarke
    • 2
  • T. P. O'Dwyer
    • 1
  1. 1.Department of Otolaryngology, The Children's Hospital, Temple Street, Dublin l, IrelandIE
  2. 2.Department of Paediatrics, George's Hall, The Children's Hospital, Temple Street, Dublin l, Ireland Tel. Fax: 01-8745545IE