European Journal of Pediatrics

, Volume 172, Issue 6, pp 747–751

Neonatal anthropometrics and correlation to childhood obesity—data from the Danish Children’s Obesity Clinic

  • Ulrik Lausten-Thomsen
  • Dorthe Sadowa Bille
  • Ida Nässlund
  • Lise Folskov
  • Torben Larsen
  • Jens-Christian Holm
Original Article

DOI: 10.1007/s00431-013-1949-z

Cite this article as:
Lausten-Thomsen, U., Bille, D.S., Nässlund, I. et al. Eur J Pediatr (2013) 172: 747. doi:10.1007/s00431-013-1949-z

Abstract

Recent evidence has demonstrated the prenatal initiation of childhood obesity as epidemiological studies and animal studies have illustrated the effect of the intrauterine milieu for subsequent development of childhood obesity. This study investigates the relationship between severe childhood obesity and the preceding in utero conditions expressed by birth weight and birth length, birth-weight-for-gestational-age and neonatal ponderal index in a Danish cohort of 1,171 severely obese children (median age 11.48 years, range 3.13 to 17.98 years) with a mean body mass index-standard derivation score (BMI-SDS) of +2.96 (range +1.65 to +9.72) treated in our national referral centre. In a linear general regression model adjusted for socioeconomic status and breastfeeding duration, a significant linear correlation between BMI-SDS at time of enrolment and both birth weight (p, 3.8 × 10−6) and birth length (p, 6.1 × 10−4), birth-weight-for-gestational-age (p, 4.3 × 10−7) and the neonatal ponderal index (p, 0.02) was demonstrated. Duration of breastfeeding, however, was not found to be significant for either the BMI-SDS/BW or the BMI-SDS/BL correlation. Conclusion: These results indicate that the prenatal period can be considered as a potential window of opportunity for prevention of childhood overweight and obesity and anthropological measurements may in theory be used to help identify neonates at high risk for developing childhood obesity.

Keywords

Birth weightChildhood obesityNeonatal ponderal indexDOHaD (developmental origins of health and disease)

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Ulrik Lausten-Thomsen
    • 1
  • Dorthe Sadowa Bille
    • 1
  • Ida Nässlund
    • 2
  • Lise Folskov
    • 1
  • Torben Larsen
    • 2
  • Jens-Christian Holm
    • 1
    • 3
  1. 1.The Children’s Obesity Clinic, Department of PaediatricsCopenhagen University Hospital HolbaekHolbaekDenmark
  2. 2.Department of Gynaecology and ObstetricsCopenhagen University Hospital HolbaekHolbaekDenmark
  3. 3.Institute of Gynaecology, Obstetrics and Paediatrics, the Medical FacultyUniversity of CopenhagenCopenhagenDenmark