European Journal of Pediatrics

, Volume 171, Issue 7, pp 1127–1131

2009 H1N1: risk factors for hospitalization in a matched case-control study

  • Cristian Launes
  • Juan-José García-García
  • Aina Martínez-Planas
  • Fernando Moraga
  • Itziar Astigarraga
  • Javier Arístegui
  • Javier Korta
  • Concepción Salado
  • José M. Quintana
  • Núria Soldevila
  • Àngela Domínguez
  • the CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Short Communication

DOI: 10.1007/s00431-012-1716-6

Cite this article as:
Launes, C., García-García, JJ., Martínez-Planas, A. et al. Eur J Pediatr (2012) 171: 1127. doi:10.1007/s00431-012-1716-6

Abstract

In order to compare sociodemographical data and preexisting risk medical conditions in patients requiring hospital admission for 2009 pandemic influenza A (H1N1) virus infection and those managed on an outpatient basis, a prospective observational, matched case-control study in 36 hospitals of the Spanish National Health Service was conducted from July 2009 to February 2010. Cases were patients aged 6 months to 18 years hospitalized for influenza syndrome, in whom 2009 influenza A (H1N1) virus infection was confirmed using real-time reverse-transcription polymerase chain reaction. Controls were patients aged 6 months to 18 years with confirmed 2009 influenza A (H1N1) infection managed on an outpatient basis. There were 195 cases and 184 controls. In a multivariate model, hospitalization was more frequent in children aged <2 years (odds ratio (OR), 13.8; 95% confidence interval (CI), 1.7–106.4), those with neurological and/or neuromuscular diseases (OR, 3.0; 95% CI, 1.1–8.2), and those whose parents had less than a secondary educational level (OR, 2.7; 95% CI, 1.4–5.2). Children aged <2 years, children with neurological diseases, and children from families with a lower educational status had a higher risk of hospitalization due to influenza A (H1N1) 2009 infection.

Keywords

Influenza A virus Children Risk factors Hospitalization Pediatrics 

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Cristian Launes
    • 1
  • Juan-José García-García
    • 1
  • Aina Martínez-Planas
    • 1
  • Fernando Moraga
    • 2
  • Itziar Astigarraga
    • 3
  • Javier Arístegui
    • 4
  • Javier Korta
    • 5
  • Concepción Salado
    • 6
  • José M. Quintana
    • 7
    • 9
  • Núria Soldevila
    • 9
  • Àngela Domínguez
    • 8
    • 9
  • the CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
  1. 1.Paediatrics Department, Hospital Sant Joan de DéuUniversity of BarcelonaBarcelonaSpain
  2. 2.Paediatrics Department, Hospital Vall d’HebrónAutonomous University of BarcelonaBarcelonaSpain
  3. 3.Paediatrics DepartmentHospital Universitario de CrucesBizkaiaSpain
  4. 4.Paediatrics DepartmentHospital Universitario de BasurtoBizkaiaSpain
  5. 5.Paediatrics DepartmentHospital Universitario de DonostiaGuipuzkoaSpain
  6. 6.Paediatrics DepartmentHospital Universitario de ÁlavaAlavaSpain
  7. 7.Research UnitHospital Galdakao-UsansoloBizkaiaSpain
  8. 8.Department of Public HealthUniversity of BarcelonaBarcelonaSpain
  9. 9.CIBER Epidemiología y Salud PúblicaBarcelonaSpain

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