European Journal of Pediatrics

, Volume 171, Issue 8, pp 1185–1191

Growth, nutritional status, and signs of rickets in 0–5-year-old children in a Kashin–Beck disease endemic area of Central Tibet

  • Shancy Rooze
  • Michèle Dramaix-Wilmet
  • Françoise Mathieu
  • Pascale Bally
  • Dikki Yangzom
  • Jin Zhong Li
  • Philippe Goyens
Original Article

DOI: 10.1007/s00431-012-1699-3

Cite this article as:
Rooze, S., Dramaix-Wilmet, M., Mathieu, F. et al. Eur J Pediatr (2012) 171: 1185. doi:10.1007/s00431-012-1699-3

Abstract

In order to describe the growth of 0–5-year-old Tibetan children living in a Kashin–Beck disease (KBD) endemic rural area and to examine the relationship between anthropometric indicators and clinical signs of rickets, we analyzed the baseline data of a cohort of 668 children enrolled in a prospective program of calcium and vitamin D supplementation. Tibetan children suffer from growth retardation. Z score of weight-for-age, height-for-age, weight-for-height was below −2 in 32.5%, 27.7%, and 12.1% of the children, respectively. Clinical signs of severe rickets are highly prevalent. Underweight, stunting, and clinical rickets increases with age. Prevalence of malnutrition was higher in the presence of signs of rickets. The proportion of children with a head circumference Z score < -2 was lowest when signs of rickets were observed. Conclusion: Stunting and underweight are frequent and probably associated with rickets.

Keywords

Underweight Stunting Wasting Infants 

Abbreviations

HC

Head circumference

KBD

Kashin–Beck disease

MUAC

Mid upper arm circumference

P25

25th percentile

P50

50th percentile

P75

75th percentile

SD

Standard deviation

TAR

Tibet Autonomous Region

WHO

World Health Organization

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Shancy Rooze
    • 1
  • Michèle Dramaix-Wilmet
    • 2
  • Françoise Mathieu
    • 3
  • Pascale Bally
    • 3
  • Dikki Yangzom
    • 4
  • Jin Zhong Li
    • 5
  • Philippe Goyens
    • 1
  1. 1.Nutrition and Metabolism UnitUniversity Children’s Hospital Queen FabiolaBrusselsBelgium
  2. 2.Department of Biostatistics, School of Public HealthUniversité Libre de BruxellesBrusselsBelgium
  3. 3.Kashin–Beck Disease FundGentBelgium
  4. 4.Kashin–Beck Disease FoundationLhasaPeople’s Republic of China
  5. 5.Centre for Disease Control and PreventionLhasaPeople’s Republic of China