European Journal of Pediatrics

, 168:267

Human papilloma virus (HPV) infection in children and adolescents

  • Ioannis N. Mammas
  • George Sourvinos
  • Demetrios A. Spandidos

DOI: 10.1007/s00431-008-0882-z

Cite this article as:
Mammas, I.N., Sourvinos, G. & Spandidos, D.A. Eur J Pediatr (2009) 168: 267. doi:10.1007/s00431-008-0882-z


Human papilloma viruses (HPV) are common pathogens associated with a wide range of cutaneous and mucosal infections in childhood. Different HPV types can cause common warts, genital warts, low-grade as well as high-grade squamous intraepithelial lesions. Anogenital warts represent an issue with legal and clinical implications and evaluation of children for the possibility of sexual abuse should be considered in all cases. Recurrent respiratory papillomatosis has also been associated with HPV infection in a variety of studies. The recently introduced HPV vaccination is expected to prevent HPV-related cervical cancer in adulthood; however, HPV infection will continue to affect children.


HPV infectionChildrenWartsRecurrent papillomatosisCervical neoplasiaHPV vaccine



human papilloma virus


squamous intraepithelial lesion


recurrent respiratory papillomatosis

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Ioannis N. Mammas
    • 1
  • George Sourvinos
    • 1
  • Demetrios A. Spandidos
    • 1
  1. 1.Department of Virology, School of MedicineUniversity of CreteCreteGreece