European Journal of Pediatrics

, 166:825

Clinical application of wireless capsule endoscopy in pediatric patients for suspected small bowel diseases

  • Zhi-Zheng Ge
  • Hai-Ying Chen
  • Yun-Jie Gao
  • Jing-Li Gu
  • Yun-Biao Hu
  • Shu-Dong Xiao
Original Paper

DOI: 10.1007/s00431-006-0331-9

Cite this article as:
Ge, ZZ., Chen, HY., Gao, YJ. et al. Eur J Pediatr (2007) 166: 825. doi:10.1007/s00431-006-0331-9

Abstract

Capsule endoscopy (CE) has been demonstrated to be safe and well tolerated in adults with suspicion of small intestinal diseases with negative results of gastroscopy and colonoscopy. However, its value in pediatric patients has not yet been well studied. This study aimed to evaluate the results and safety of CE in pediatric patients with suspicion of small bowel disorders. There were 16 consecutive children and adolescents (12 boys, 4 girls) and 15 adults (9 men, 6 women) referred to us for suspected small bowel diseases from August 2002 to September 2005. Among the pediatrics, six patients were less than 10 years old. Technique for capsule placement, gastric transit time, small bowel transit time, excretion time of capsule endoscopy, capsule findings, and complications were recorded. All 16 pediatric patients described that the capsule was easy to swallow except for three children. Finally we delivered the capsule under gastroscopy with overtube for these three children. No capsule retention occurred during our study. Median recording time was 7 h 44 min (range 6 h 51 min–9 h 11 min). Median gastric transit time was 83.5 min (range 4–296 min). Median small bowel transit time was 270 min (range 142–484 min).Median excretion time of capsule was 33.9 h (range 12–96 h). There was no significant difference in excretion time of capsule, gastric transit time and small bowel transit time between pediatric patients and adult patients (P > 0.05). CE was positive in 12 patients, including Crohn’s disease (4), hemangioma (2), angiodysplasia (2), Meckel diverticulum (1), polyp (1), aphthous ulcer in ascending colon (1), and cobblestone appearance of ileal mucosa. CE has been performed safely in a small series of pediatric patients after ingestion or endoscopic placement of the capsule. The high yield of abnormal findings was comparable to those of adult patients.

Keywords

Wireless capsule endoscopy Pediatric gastroenterology Small bowel diseases Gastric transit time Small bowel transit time 

Abbreviations

CE

capsule endoscopy

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Zhi-Zheng Ge
    • 1
  • Hai-Ying Chen
    • 1
  • Yun-Jie Gao
    • 1
  • Jing-Li Gu
    • 1
  • Yun-Biao Hu
    • 1
  • Shu-Dong Xiao
    • 1
  1. 1.Department of Gastroenterology, Shanghai Institute of Digestive Disease, Renji HospitalShanghai Jiaotong University School of MedicineShanghaiChina

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