Original Paper

European Journal of Pediatrics

, Volume 164, Issue 3, pp 141-145

First online:

Plasma aldosterone levels in the 1st week of life in infants of less than 30 weeks gestation

  • David BourchierAffiliated withNewborn Intensive Care Unit, Waikato Hospital Email author 

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Plasma aldosterone levels were measured in 50 infants of less than 30 weeks gestation at 24 h (D1) and 7 days (D7). The relationship between the plasma aldosterone level and a number of clinical and biochemical variables was explored. Plasma aldosterone levels ranged from 1000 to 30000 pmol/l and were inversely correlated with the severity of illness (D1 or D7), serum sodium (D7) and 24 h sodium intake (D1). No correlation with the serum potassium level was noted. Conclusion:Plasma aldosterone levels in this extremely premature cohort were significantly greater than those reported in more mature infants. Important determinants were severity of illness and sodium homeostasis.


Plasma aldosterone Preterm