, Volume 162, Issue 12, pp 891-892
Date: 21 Oct 2003

Rhabdomyolysis in a patient with Kawasaki disease

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A previously healthy, 8-month-old boy suffered from Kawasaki disease with rhabdomyolysis.

Although Kawasaki disease (KD) is a systemic vasculitis affecting multiple organ systems, muscle involvement has rarely been reported [1, 2, 3, 4, 5,6]. This report describes rhabdomyolysis in a patient with KD.

A previously healthy, 8-month-old boy was referred to another hospital because of a 5-day history of high-grade fever, cervical lymph node swelling, and exanthema. The patient was transferred to our hospital because of elevated creatine kinase (CK) levels. The patient did not take any anti-inflammatory drugs including ibuprofen before admission. Upon admission, physical examination revealed bilateral conjunctivitis, a strawberry-like tongue, enlarged cervical lymph nodes, polymorphic truncal rash and oedema of the peripheral extremities. His vital signs were as follows: body temperature 40.3°C; blood pressure 102/48 mmHg; and pulse rate 140 beats/min. The body weight was 9.6 kg (-0.4 kg befo ...