Brain Structure and Function

, Volume 218, Issue 1, pp 105–121

Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study

  • Juan Martino
  • Philip C. De Witt Hamer
  • Mitchel S. Berger
  • Michael T. Lawton
  • Christine M. Arnold
  • Enrique Marco de Lucas
  • Hugues Duffau
Original Article

DOI: 10.1007/s00429-012-0386-5

Cite this article as:
Martino, J., De Witt Hamer, P.C., Berger, M.S. et al. Brain Struct Funct (2013) 218: 105. doi:10.1007/s00429-012-0386-5

Abstract

The anatomy of the perisylvian component of the superior longitudinal fasciculus (SLF) has recently been reviewed by numerous diffusion tensor imaging tractography (DTI) studies. However, little is known about the exact cortical terminations of this tract. The aim of the present work is to isolate the different subcomponents of this tract with fiber dissection and DTI tractography, and to identify the exact cortical connections. Twelve postmortem human hemispheres (6 right and 6 left) were dissected using the cortex-sparing fiber dissection. In addition, three healthy brains were analyzed using DTI-based tractography software. The different components of the perisylvian SLF were isolated and the fibers were followed until the cortical terminations. Three segments of the perisylvian SLF were identified: (1) anterior segment, connecting the supramarginal gyrus and superior temporal gyrus with the precentral gyrus, (2) posterior segment, connecting the posterior portion of the middle temporal gyrus with the angular gyrus, and (3) long segment of the arcuate fasciculus that connects the middle and inferior temporal gyri with the precentral gyrus and posterior portion of the inferior and middle frontal gyri. In the present study, three different components of the perisylvian SLF were identified. For the first time, our dissections revealed that each component was connected to a specific cortical area within the frontal, parietal and temporal lobes. By accurately depicting not only the trajectory but also cortical connections of this bundle, it is possible to develop new insights into the putative functional role of this tract.

Keywords

Arcuate fasciculusDTI tractographyFiber dissectionSuperior longitudinal fasciculus

Abbreviations

AF

Arcuate fasciculus

AG

Angular gyrus

DTI

Diffusion tensor imaging

IES

Intraoperative electrical stimulation

IFG

Inferior frontal gyrus

ITG

Inferior temporal gyrus

MFG

Middle frontal gyrus

PCG

Precentral gyrus

SF

Sylvian fissure

SLF

Superior longitudinal fasciculus

SMG

Supramarginal gyrus

SPL

Superior parietal lobe

STG

Superior temporal gyrus

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Juan Martino
    • 1
  • Philip C. De Witt Hamer
    • 2
  • Mitchel S. Berger
    • 3
  • Michael T. Lawton
    • 3
  • Christine M. Arnold
    • 3
  • Enrique Marco de Lucas
    • 4
  • Hugues Duffau
    • 5
    • 6
  1. 1.Department of Neurological SurgeryHospital Universitario Marqués de Valdecilla and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV)SantanderSpain
  2. 2.Department of Neurological SurgeryVU University Medical CenterAmsterdamThe Netherlands
  3. 3.Department of Neurological SurgeryUniversity of California San Francisco (UCSF)San FranciscoUSA
  4. 4.Department of RadiologyHospital Universitario Marqués de Valdecilla and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV)SantanderSpain
  5. 5.Department of Neurological SurgeryHôpital Gui de Chauliac, CHU MontpellierMontpellierFrance
  6. 6.INSERM U1051, Institute for Neurosciences of Montpellier, Hôpital Saint EloiMontpellierFrance