Virchows Archiv

, Volume 441, Issue 1, pp 88–92

Vibrio vulnificus infection in patients with liver disease: report of five autopsy cases

  • Yongxin Chen
  • Toshimi Satoh
  • Osamu Tokunaga
Original Article

DOI: 10.1007/s00428-002-0613-1

Cite this article as:
Chen, Y., Satoh, T. & Tokunaga, O. Virchows Arch (2002) 441: 88. doi:10.1007/s00428-002-0613-1

Abstract.

Five autopsy cases of Vibrio vulnificus infection with liver disease are reported. All five patients ate raw seafood 24 h before the onset of illness. The clinical presentation was of primary septicemia, with positive cultures in both the blood and cutaneous lesions. Stool cultures were positive for the organism in one patient with gastrointestinal symptoms. Autopsy examination revealed liver cirrhosis in three cases and alcoholic liver disease in two; all showed portal hypertension. Gastrointestinal mucosal changes were seen in four patients: edema, hemorrhagic necrosis, and lymphocyte infiltration. One case was of an human immunodeficiency virus infected patient in which histology showed a rare intestinal disease, phlegmonous colitis. We believe this is the first description of a case of concomitant phlegmonous enterocolitis and V. vulnificus infection. Patients with liver disease should be warned about the possibility of life-threatening infections and complications associated with the consumption of raw seafood.

Vibrio vulnificus Liver disease Phlegmonous colitis

Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  • Yongxin Chen
    • 1
  • Toshimi Satoh
    • 1
  • Osamu Tokunaga
    • 1
  1. 1.Department of Pathology, Saga Medical School, Nabeshima 5-1-1, Saga 849-8501, JapanJapan