Development Genes and Evolution

, Volume 219, Issue 11, pp 613–618

Expression of Hox4 during development of the pentamerous juvenile sea star, Parvulastra exigua

Short Communication

DOI: 10.1007/s00427-010-0318-4

Cite this article as:
Cisternas, P. & Byrne, M. Dev Genes Evol (2009) 219: 613. doi:10.1007/s00427-010-0318-4


Expression of Hox4 during development of the bilateral larva and pentameral juvenile sea star was investigated in Parvulastra exigua. The role of Hox4, possibly the anterior-most gene in the echinoderm Hox cluster, in the formation of the echinoderm adult body plan has not been examined previously. In the larva of P. exigua, PeHox4 is expressed in the developing coeloms—the anterior and the right and left coeloms that generate the aboral and oral coeloms of the juvenile. At the rudiment stage, PeHox4 was expressed in the five primary lobes of the hydrocoel that give rise to primary podia, the foundation of the adult body plan. This suggests a role for this gene in the development of the echinoderm body plan. In contrast to other bilaterians, Hox4 was not expressed in the developing asteroid central nervous system.


Hox4 expressionBody planParvulastra exiguaAsteroidEchinoderm

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© Springer-Verlag 2010

Authors and Affiliations

  1. 1.School of Medical Sciences, Bosch InstituteThe University of SydneySydneyAustralia
  2. 2.School of Biological SciencesThe University of SydneySydneyAustralia