Development Genes and Evolution

, Volume 213, Issue 7, pp 363–367

Complementary expression of AP-2 and AP-2rep in ectodermal derivatives of Xenopus embryos

Authors

  • Masanori Gotoh
    • Graduate School of Science and TechnologyNiigata University
  • Yumi Izutsu
    • Graduate School of Science and TechnologyNiigata University
    • Department of Biology, Faculty of ScienceNiigata University
Expression Note

DOI: 10.1007/s00427-003-0336-6

Cite this article as:
Gotoh, M., Izutsu, Y. & Maéno, M. Dev Genes Evol (2003) 213: 363. doi:10.1007/s00427-003-0336-6

Abstract

In an attempt to define the pattern of developmental expression of AP-2rep and AP-2 in Xenopus embryos, we cloned a Xenopus AP-2rep cDNA. The AP-2rep message was localized in the organizer region at the gastrula stage whereas AP-2 was expressed ventro-laterally in the animal hemisphere. Later, AP-2rep was expressed in the entire neural tissue at the neurula stage while AP-2 was predominantly expressed in the cranial neural crest areas. The endogenous expression of AP-2 in the neural crest area was diminished by ectopic injection of AP-2rep RNA, suggesting a role for AP-2rep in the differentiation of neural tissues by restricting the expression of AP-2 in the Xenopus embryo.

Keywords

Activator protein-2 KLF-12 Telencephalon Neural crest Repressor

Copyright information

© Springer-Verlag 2003