Development Genes and Evolution

, Volume 211, Issue 11, pp 555–558

Gdf5 is expressed in the developing skeleton of median fins of late-stage zebrafish, Daniorerio

  • Patricia L. Crotwell
  • Tim G. Clark
  • Paula M. Mabee
Short Communication

DOI: 10.1007/s00427-001-0186-z

Cite this article as:
Crotwell, P.L., Clark, T.G. & Mabee, P.M. Dev Genes Evol (2001) 211: 555. doi:10.1007/s00427-001-0186-z

Abstract.

The dynamic expression of Gdf5 is described in the developing skeleton of the median fins of late-stage zebrafish, Danio rerio (6–45 days post-fertilization). In situ hybridization revealed expression in the mesenchyme between cartilage condensations of the endoskeletal supports of the dorsal, anal, and caudal fins. As development proceeds, the expression domains expand distally to surround tips of developing cartilages, consistent with a role in cartilage growth and differentiation. Gdf5 is later expressed in the segmenting regions of the dorsal and anal fin radials, which may indicate a role in segmentation. After growth to 7.5 mm, Gdf5 transcripts can no longer be detected in any of the median fins, nor is Gdf5 expression reinitiated in later development of the median fin skeleton.

Gdf5 Median fin Danio rerio Skeletal development In situ hybridization

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Patricia L. Crotwell
    • 1
  • Tim G. Clark
    • 2
  • Paula M. Mabee
    • 1
  1. 1.Department of Biology, University of South Dakota, Vermillion, SD 57069, USA
  2. 2.Division of Basic Biomedical Sciences, University of South Dakota, Vermillion, SD 57069, USA