Pflügers Archiv

, Volume 447, Issue 5, pp 629–635

Organic anion transport is the primary function of the SLC17/type I phosphate transporter family

The ABC of Solute Carriers Guest Editor: Matthias A. Hediger

DOI: 10.1007/s00424-003-1087-y

Cite this article as:
Reimer, R.J. & Edwards, R.H. Pflugers Arch - Eur J Physiol (2004) 447: 629. doi:10.1007/s00424-003-1087-y

Abstract

Recently, molecular studies have determined that the SLC17/type I phosphate transporters, a family of proteins initially characterized as phosphate carriers, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitter glutamate to the degradation and metabolism of glycoproteins.

Keywords

Neurotransmitter transporterOrganic anion transportSialinType I phosphate transporterVesicular glutamate transporter

Copyright information

© Springer-Verlag  2004

Authors and Affiliations

  1. 1.Department of Neurology and Neurological SciencesStanford University School of MedicineStanfordUSA
  2. 2.Departments of Neurology and Physiology, Graduate Programs in Neuroscience and Cell BiologyUniversity of CaliforniaSan FranciscoUSA