Langenbeck's Archives of Surgery

, Volume 397, Issue 6, pp 869–879

Surgical management of proximal bile duct cancers

Review Article

DOI: 10.1007/s00423-012-0928-6

Cite this article as:
LaFemina, J. & Jarnagin, W.R. Langenbecks Arch Surg (2012) 397: 869. doi:10.1007/s00423-012-0928-6



Tumors arising from the proximal biliary tree remain particularly challenging with respect to their evaluation and treatment. Complete resection with negative histologic margins is the most effective treatment modality.


However, the majority of patients are not candidates for surgery.


Over the last decades, advances have evolved to improve resectability and morbidity after major liver and bile duct resection. However, these disease processes still pose a management challenge. Herein, we provide an overview of proximal bile duct cancers, hilar cholangiocarcinoma (HCCa) and intrahepatic cholangiocarcinoma (ICCa).


Hilar cholangiocarcinomaIntrahepatic cholangiocarcinoma

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkUSA