Modified radical lymphadenectomy (D1.5) for T2–3 gastric cancer
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The operative mortality in gastric cancer surgery has been reported to be higher with D2 lymphadenectomy than with D1 in the West. The modified radical lymphadenectomy (D1.5) may be safer than D2 under these circumstances. This study was aimed to determine whether D1.5 would deteriorate long-term survival as compared with D2.
Since the concept of the extent of lymphadenectomy varied among the surgeons, 461 patients who underwent curative gastrectomy for T2–4 gastric adenocarcinoma were retrospectively categorized into three groups according to the surgeon: D1 with dissection along the left gastric and common hepatic arteries (D1.5); lymphadenectomy between D1.5 and D2; D2 or more extended dissection.
No differences were found in the survival rates among the three groups within each of the T2a, T2b, and T3 categories. According to a multivariate analysis using Cox’s proportional hazard model, the classification according to the surgeons had no survival impact (p>0.8).
D1.5 lymphadenectomy resulted in a survival rate that was almost equal to that of D2. The use of D1.5 instead of D2 can be an attractive option to be compared with D1 in future trials.
- Modified radical lymphadenectomy (D1.5) for T2–3 gastric cancer
Langenbeck's Archives of Surgery
Volume 390, Issue 5 , pp 397-402
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- Modified radical lymphadenectomy
- D1.5 dissection
- D2 dissection
- Gastric cancer
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