Langenbeck's Archives of Surgery

, Volume 389, Issue 6, pp 485–491

Volume replacement and microhemodynamic changes in polytrauma

Current Concepts in Clinical Surgery

DOI: 10.1007/s00423-004-0473-z

Cite this article as:
Vollmar, B. & Menger, M.D. Langenbecks Arch Surg (2004) 389: 485. doi:10.1007/s00423-004-0473-z


Though fluid administration is one of the most basic concepts in resuscitation, there is ongoing controversy and continuing research on the definition of the ideal fluid for resuscitation of trauma and hemorrhage and for intraoperative volume support. In general, crystalloids and colloids, as well as blood, blood substitutes and oxygen therapeutics, are available. This report briefly revisits the physiological mechanisms underlying resuscitation with crystalloids and colloids, emphasizing colloid-supplemented resuscitation with hypertonic saline. Finally, potential applications of oxygen therapeutics are briefly considered.


Microcirculation Nutritive perfusion Cell–cell interaction Crystalloids Colloids 

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  1. 1.Department of Experimental SurgeryUniversity of RostockRostockGermany
  2. 2.Institute of Clinical-Experimental SurgeryUniversity of SaarlandHomburg-SaarGermany

Personalised recommendations