Biological Cybernetics

, Volume 85, Issue 2, pp 145–157

Evaluating causal relations in neural systems: Granger causality, directed transfer function and statistical assessment of significance

Authors

  • Maciej Kamiński
    •  Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Rd., Boca Raton, FL 33431, USA
  • Mingzhou Ding
    •  Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Rd., Boca Raton, FL 33431, USA
  • Wilson A. Truccolo
    •  Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Rd., Boca Raton, FL 33431, USA
  • Steven L. Bressler
    •  Center for Complex Systems and Brain Sciences, Florida Atlantic University, 777 Glades Rd., Boca Raton, FL 33431, USA

DOI: 10.1007/s004220000235

Cite this article as:
Kamiński, M., Ding, M., Truccolo, W. et al. Biol Cybern (2001) 85: 145. doi:10.1007/s004220000235

Abstract.

 We consider the question of evaluating causal relations among neurobiological signals. In particular, we study the relation between the directed transfer function (DTF) and the well-accepted Granger causality, and show that DTF can be interpreted within the framework of Granger causality. In addition, we propose a method to assess the significance of causality measures. Finally, we demonstrate the applications of these measures to simulated data and actual neurobiological recordings.

Copyright information

© Springer-Verlag Berlin Heidelberg 2001