Evaluating causal relations in neural systems: Granger causality, directed transfer function and statistical assessment of significance
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- Kamiński, M., Ding, M., Truccolo, W. et al. Biol Cybern (2001) 85: 145. doi:10.1007/s004220000235
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We consider the question of evaluating causal relations among neurobiological signals. In particular, we study the relation between the directed transfer function (DTF) and the well-accepted Granger causality, and show that DTF can be interpreted within the framework of Granger causality. In addition, we propose a method to assess the significance of causality measures. Finally, we demonstrate the applications of these measures to simulated data and actual neurobiological recordings.