Biological Cybernetics

, Volume 89, Issue 5, pp 388–396

Modeling coincidence detection in nucleus laminaris

Authors

  • Victor Grau-Serrat
    • Department of Electrical and Computer EngineeringUniversity of Maryland
    • Institute for Systems ResearchUniversity of Maryland
  • Catherine E. Carr
    • Department of BiologyUniversity of Maryland
    • Program in Neuroscience and Cognitive SciencesUniversity of Maryland
    • Department of Electrical and Computer EngineeringUniversity of Maryland
    • Department of BiologyUniversity of Maryland
    • Institute for Systems ResearchUniversity of Maryland
    • Program in Neuroscience and Cognitive SciencesUniversity of Maryland
Article

DOI: 10.1007/s00422-003-0444-4

Cite this article as:
Grau-Serrat, V., Carr, C. & Simon, J. Biol. Cybern. (2003) 89: 388. doi:10.1007/s00422-003-0444-4

Abstract.

A biologically detailed model of the binaural avian nucleus laminaris is constructed, as a two-dimensional array of multicompartment, conductance-based neurons, along tonotopic and interaural time delay (ITD) axes. The model is based primarily on data from chick nucleus laminaris. Typical chick-like parameters perform ITD discrimination up to 2 kHz, and enhancements for barn owl perform ITD discrimination up to 6 kHz. The dendritic length gradient of NL is explained concisely. The response to binaural out-of-phase input is suppressed well below the response to monaural input (without any spontaneous activity on the opposite side), implicating active potassium channels as crucial to good ITD discrimination.

Abbreviations

NL

Nucleus Laminaris

NM

Nucleus Magnocellularis

ITD

Interaural Time Difference

BF

Best Frequency

Copyright information

© Springer-Verlag Berlin Heidelberg 2003