European Journal of Applied Physiology and Occupational Physiology

, Volume 77, Issue 3, pp 206–211

Acute hormonal responses to heavy resistance exercise in younger and older men

  • William J. Kraemer
  • Keijo Häkkinen
  • Robert U. Newton
  • Matthew McCormick
  • Bradley C. Nindl
  • Jeff S. Volek
  • Lincoln A. Gotshalk
  • Steven J. Fleck
  • Wayne W. Campbell
  • Scott E. Gordon
  • Peter A. Farrell
  • William J. Evans
ORIGINAL ARTICLE

DOI: 10.1007/s004210050323

Cite this article as:
Kraemer, W., Häkkinen, K., Newton, R. et al. Eur J Appl Physiol (1998) 77: 206. doi:10.1007/s004210050323

Abstract

The purpose of this investigation was to examine the acute responses of several hormones [total and free testosterone (TT and FT, respectively), adrenocorticotropic hormone (ACTH), cortisol (C), growth hormone (GH), and insulin (INS)] to a single bout of heavy resistance exercise (HRE). Eight younger [30-year (30y) group] and nine older [62-year (62y) group] men matched for general physical characteristics and activity levels performed four sets of ten repetitions maximum (RM) squats with 90 s rest between sets. Blood samples were obtained from each subject via an indwelling cannula with a saline lock pre-exercise, immediately post-exercise (IP), and 5, 15 and 30 min post-exercise. Levels of TT, FT, ACTH, C and lactate significantly increased after HRE for both groups. Pre-HRE pairwise differences between groups were noted only for FT, while post-HRE pairwise differences were found for TT, FT, GH, glucose and lactate. Area under the curve analysis showed that the 30y group had a significantly higher magnitude of increase over the entire recovery period (IP, 5, 15, and 30 min post-exercise) for TT, FT, ACTH and GH. Few changes occurred in the INS response with the only change being that the 62y group demonstrated a decrease IP. Lactate remained elevated at 30 min post-HRE. This investigation demonstrates that age-related differences occur in the endocrine response to HRE, and the most striking changes appear evident in the FT response to HRE in physically active young and older men.

Key words AgingNeuroendocrineResistance exerciseGrowth factors

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • William J. Kraemer
    • 1
  • Keijo Häkkinen
    • 2
  • Robert U. Newton
    • 3
  • Matthew McCormick
    • 1
  • Bradley C. Nindl
    • 1
  • Jeff S. Volek
    • 1
  • Lincoln A. Gotshalk
    • 1
  • Steven J. Fleck
    • 1
  • Wayne W. Campbell
    • 1
  • Scott E. Gordon
    • 1
  • Peter A. Farrell
    • 1
  • William J. Evans
    • 1
  1. 1.Noll Physiological Research Center and Laboratory for Sports Medicine, Pennsylvania State University, 21 REC Bldg, University Park, PA 16802, USAUS
  2. 2.Department of Biology of Physical Activity, The University of Jyvaskyla, Jyvaskyla, FinlandFI
  3. 3.Department of Exercise Science and Sport Management, Southern Cross University, Lismore, NSW, AustraliaAU