Graefe's Archive for Clinical and Experimental Ophthalmology

, Volume 251, Issue 1, pp 19–25

Six-month visual prognosis in eyes with submacular hemorrhage secondary to age-related macular degeneration or polypoidal choroidal vasculopathy

  • Chui Ming Gemmy Cheung
  • Mayuri Bhargava
  • Li Xiang
  • Ranjana Mathur
  • Chan Choi Mun
  • Doric Wong
  • Tien Yin Wong
Retinal Disorders

DOI: 10.1007/s00417-012-2029-1

Cite this article as:
Cheung, C.M.G., Bhargava, M., Xiang, L. et al. Graefes Arch Clin Exp Ophthalmol (2013) 251: 19. doi:10.1007/s00417-012-2029-1

Abstract

Background

To determine clinical or imaging prognostic features for visual outcome in eyes with submacular hemorrhage secondary to age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV).

Methods

A prospective case series of 11 eyes from 11 patients with submacular hemorrhage secondary to AMD or PCV. All participants had measurement of clinical characteristics, fundus angiogram, and indocyanine green angiography, spectral domain optical coherence tomography (OCT, Cirrus, Zeiss) at baseline and 6 months.

Results

Median visual acuity improved from 20/132 to 20/63 at month 6. The median improvement in vision was 0.20 LogMAR units. Proportion of eyes with best-corrected visual acuity (BCVA) ≥1.0 increased from 6/11 (54.5 %) at baseline to 8/11 (72.7 %) at month 6. Eyes with BCVA > 1.0 were more likely to have larger area of hemorrhage and thinner subfoveal neurosensory retinal thickness at baseline and at month 6.

Conclusions

Thinner neurosensory retina demonstrated on OCT at baseline may be a useful prognostic sign for limited visual recovery.

Keywords

Submacular hemorrhageOptical coherence tomographyPrognosisAge-related macular degeneration

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Chui Ming Gemmy Cheung
    • 1
    • 2
    • 3
  • Mayuri Bhargava
    • 1
    • 2
    • 3
  • Li Xiang
    • 2
  • Ranjana Mathur
    • 1
  • Chan Choi Mun
    • 1
  • Doric Wong
    • 1
  • Tien Yin Wong
    • 1
    • 2
    • 3
    • 4
  1. 1.Singapore National Eye CentreSingaporeSingapore
  2. 2.Singapore Eye Research InstituteSingaporeSingapore
  3. 3.Department of Ophthalmology, Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore
  4. 4.Centre for Eye Research AustraliaUniversity of Melbourne, Royal Victorian Eye and Ear HospitalMelbourneAustralia