Date: 06 Jan 2012

Macular oedema in Kawasaki syndrome

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Introduction

Kawasaki syndrome (KS) is a rare disorder, which most frequently affects infants younger than 5 years of age. The disease is a unique form of acute systemic vasculitis, which affects primarily medium-sized, and particularly the coronary arteries. Although the pathophysiology of KS is not fully understood, evidence points to its induction by a specific infectious agent. A predisposition for the disease is presumed [1]. Clinically, KS is manifested as an acute febrile form of vasculitis, which may be fatal if not diagnosed at an early stage. Other signs of the disease include dilatation of the conjunctival vessels and iridocyclitis. These frequent ocular manifestations may be of diagnostic importance, since in 45% of instances the typical systemic criteria are not completely fulfilled. Although two-thirds of cases present with bilateral conjunctival injection and/or iridocyclitis, the vast majority of patients are not referred to an ophthalmologist, thereby delaying the final