Date: 04 Jun 2011

Is the peripheral retina an important site for myopic development? [Liu Y, Wildsoet C (2011) The effectof two-zone concentric bifocal spectacle lenses on refractive error development and eye growth in young chicks. Invest Ophthalmol Vis Sci 52(2):1078–1086]

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Myopia is now the most common refractive error in the world. It is reported that the prevalence of myopia ranges from 52% to 82% for Asian teenagers [1]. Emmetropization is a process which adjusts the axial length of the eye to match its refractive power in order to achieve clear vision. However, depending on the situation, this process of adjusting the axial length can induce different refractive conditions, i.e., myopia or hyperopia. Different studies have demonstrated that ocular growth is regulated by visual stimuli, and animal models have been used to show the effect of experimentally induced defocus on the axial growth of the eye. In addition, optical defocus with different signs (i.e., hyperopic and myopic) and different degrees can regulate ocular growth to produce different refractive errors. This visually guided ocular growth is not related to the visual cortex, because emmetropization is still effective after section of the optic nerve and all ciliary nerves. An interesting