Cornea

Graefe's Archive for Clinical and Experimental Ophthalmology

, Volume 249, Issue 10, pp 1515-1518

First online:

Titanium back plate for a PMMA keratoprosthesis: clinical outcomes

  • Amit TodaniAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Joseph B. CiolinoAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Jared D. AmentAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Kathryn A. ColbyAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Roberto PinedaAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Michael W. BelinAffiliated withDepartment of Ophthalmology & Vision Science, University of Arizona
  • , James V. AquavellaAffiliated withEye Institute, University of Rochester
  • , James ChodoshAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary
  • , Claes H. DohlmanAffiliated withCornea Service, Massachusetts Eye and Ear Infirmary Email author 

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Abstract

Background/Purpose

To compare the rate of retroprosthetic membrane (RPM) formation in Boston Keratoprosthesis (BKPro) with polymethyl methacrylate (PMMA) versus titanium backplates.

Design

Retrospective comparative chart review.

Methods

Multicenter study population: a total of 78 eyes with keratoprosthesis implants with either PMMA or titanium backplates were included in the study. To be included in the study, all subjects had to have completed a minimum of 6-month follow-up period. Incidence of RPM development at 6-month postoperative period was noted across the study population. PMMA and titanium backplates were then compared by their rate of association with subsequent RPM.

Results

Twenty-three out of 55 eyes (41.8%) with PMMA backplates and three out of 23 eyes (13.0%) with titanium backplates had developed an RPM at 6 months after implantation. The titanium backplates were associated with significantly less RPM formation than PMMA backplates (p = 0.014, Chi-square test).

Conclusions

Titanium seems to be associated with less RPM formation than PMMA when used as a material for the BKPro back plate.

Keywords

Boston Keratoprosthesis Keratoprosthesis KPro BKPro Retroprosthetic membrane RPM PMMA Titanium