Titanium back plate for a PMMA keratoprosthesis: clinical outcomes
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To compare the rate of retroprosthetic membrane (RPM) formation in Boston Keratoprosthesis (BKPro) with polymethyl methacrylate (PMMA) versus titanium backplates.
Retrospective comparative chart review.
Multicenter study population: a total of 78 eyes with keratoprosthesis implants with either PMMA or titanium backplates were included in the study. To be included in the study, all subjects had to have completed a minimum of 6-month follow-up period. Incidence of RPM development at 6-month postoperative period was noted across the study population. PMMA and titanium backplates were then compared by their rate of association with subsequent RPM.
Twenty-three out of 55 eyes (41.8%) with PMMA backplates and three out of 23 eyes (13.0%) with titanium backplates had developed an RPM at 6 months after implantation. The titanium backplates were associated with significantly less RPM formation than PMMA backplates (p = 0.014, Chi-square test).
Titanium seems to be associated with less RPM formation than PMMA when used as a material for the BKPro back plate.
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Graefe's Archive for Clinical and Experimental Ophthalmology
Volume 249, Issue 10 , pp 1515-1518
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Boston Keratoprosthesis
- Retroprosthetic membrane
- Industry Sectors
- Author Affiliations
- 1. Cornea Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA, 02114, USA
- 2. Department of Ophthalmology & Vision Science, University of Arizona, 4232 West Summer Ranch Place, Marana, AZ, 85658, USA
- 3. Eye Institute, University of Rochester, 210 Crittenden Blvd, Rochester, NY, 14642, USA