Original Communication

Journal of Neurology

, Volume 260, Issue 2, pp 462-469

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Future MS care: a consensus statement of the MS in the 21st Century Steering Group

  • Peter RieckmannAffiliated withDepartment of Neurology, Sozialstiftung Bamberg Hospital Email author 
  • , Alexey BoykoAffiliated withMoscow MS Center
  • , Diego CentonzeAffiliated withClinical and Research MS Center, Department of Neuroscience, Tor Vergata University
  • , Alasdair ColesAffiliated withDepartment of Neurology, Box 165, Addenbrooke’s Hospital
  • , Irina ElovaaraAffiliated withDepartment of Neurology, Tampere University Hospital and University of Tampere
  • , Eva HavrdováAffiliated withDepartment of Neurology, First Medical Faculty, Charles University
  • , Otto HommesAffiliated withEuropean Charcot Foundation
  • , Jacques LeLorierAffiliated withPavillon Masson
  • , Sarah A. MorrowAffiliated withDepartment of Neurology, Western University, LHSC-UH
    • , Celia Oreja-GuevaraAffiliated withDepartment of Neurology, Sozialstiftung Bamberg HospitalDepartment of Neurology, University Hospital San Carlos
    • , Nick RijkeAffiliated withDepartment of Neurology, Sozialstiftung Bamberg HospitalMS National Centre
    • , Sven SchipplingAffiliated withDepartment of Neurology, Sozialstiftung Bamberg HospitalDepartment of Neuroimmunology and MS Research (NIMS), Neurology Clinic, University Medical Center Zurich


The “MS in the 21st Century” initiative was established with the purpose of (1) defining how multiple sclerosis (MS) treatment and standards of care should look in the 21st century; (2) developing a minimum standard of care across the world; and (3) motivating the broad MS community to align standards of care and challenge the current treatment paradigm. The aim was to develop a consensus statement to reach and influence the broader MS community. An expert steering group from Europe and Canada—consisting of neurologists, patient advocates, a pharmacoepidemiologist/pharmacoeconomist, and representatives from national MS centers—participated in a series of workshop-driven meetings between February 2011 and 2012. After three phases of discussions, the steering group identified that the overall vision for future care of MS should be full access to personalized treatment, with reimbursement, to achieve freedom from disease. They constructed seven overall principles that support this vision: personalized care, patient engagement, commitment to research, regulatory body education and reimbursement issues, new endpoints in clinical trials, more therapy options, and MS centers of excellence. This consensus statement outlines the key aspects of the seven principles that need to be addressed. The “MS in the 21st Century Steering Group” hopes that this consensus statement acts as a call to action for healthcare providers and decision-makers to address simultaneously the overarching principles that will guide patient management in order to improve outcomes for people with MS.


Multiple sclerosis Care Management Consensus statement