, Volume 256, Issue 6, pp 1004-1006
Date: 25 Feb 2009

Closing-in behaviour in fronto-temporal dementia

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“Closing-in behaviour” (CIB) is the tendency in copying tasks (figure copying or gesture imitation) to perform very close to or even on the top of the model. This phenomenon, which has been reported in focal brain diseases (cerebral stroke, encephalitis, epilepsy) [13] and various forms of dementia [46], has been noted most commonly in Alzheimer’s disease (AD) [6]. In AD, the frequency of this behaviour increases with dementia severity [7] and with increasing complexity of the figures/gestures to copy [8, 9]. CIB has also been observed in fronto-temporal dementia (FTD) and interpreted as a sign of constructional apraxia (CA) [10]. However, the frequency and character of CIB have never been systematically investigated in FTD.

We assessed CA and CIB retrospectively in 71 patients with a diagnosis of FTD [11]. For comparison, 812 medical records of patients with AD [12] were also reviewed. All patients had completed the Milan Overall Dementia Assessment (MODA) test battery [13] at the Ne