Clinical features and associated syndromes of mal de debarquement
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To investigatethe clinical features and naturalhistory of mal de debarquement(MdD).
Retrospective casereview with follow-up questionnaireand telephone interviews.
University Neurotology Clinic.
Patients seen between1980 and 2006 who developed apersistent sensation of rocking orswaying for at least 3 days after exposureto passive motion.
Main outcome measure
Clinical features,diagnostic testing, and questionnaireresponses.
Of 64 patients(75 % women) identifiedwith MdD, 34 completed follow-upquestionnaires and interviews in2006. Most patients had normalneurological exams, ENGs andbrain MRIs. The average age of thefirst MdD episode was 39 ± 13years. A total of 206 episodes wereexperienced by 64 patients. Ofthese, 104 episodes (51 %) lasted> 1 month; 18 %, > 1 year; 15 %, > 2years; 12 %, > 4 years, and 11 %, > 5years. Eighteen patients (28 %) subsequentlydeveloped spontaneousepisodes of MdD-like symptomsafter the initial MdD episode.There was a much higher rate ofmigraine in patients who went onto develop spontaneous episodes(73 %) than in those who did not(22 %). Subsequent episodes werelonger than earlier ones in mostpatients who had multiple episodes.Re-exposure to passivemotion temporarily decreasedsymptoms in most patients (66 %).Subjective intolerance to visualmotion increased (10 % to 66 %)but self-motion sensitivity did not(37 % to 50 %) with onset of MdD.
The majority of MdDepisodes lasting longer than 3 daysresolve in less than one year but theprobability of resolution declineseach year. Many patients experiencemultiple MdD episodes. Somepatients develop spontaneousepisodes after the initial motiontriggeredepisode with migrainebeing a risk factor.
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- Clinical features and associated syndromes of mal de debarquement
Journal of Neurology
Volume 255, Issue 7 , pp 1038-1044
- Cover Date
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- Online ISSN
- D. Steinkopff-Verlag
- Additional Links
- mal de debarquement
- vestibular adaptation
- motion sensitivity
- visual motion
- Industry Sectors
- Author Affiliations
- 1. Dept. of Neurology, University of California, 710 Westwood Plaza, 951769, Los Angeles, CA 90095, USA
- 2. Dept. of Statistics, University of California, 8/25 Math Sciences Building, 95/554, Los Angeles, CA 90095-1554, USA
- 3. Dept. of Human Genetics, University of CaliforniaUCLA Hum Genetics, 957088, 6357A Gonda Cntr, Los Angeles, CA 90095-7088, USA