ORIGINAL COMMUNICATION

Journal of Neurology

, Volume 253, Issue 9, pp 1143-1146

First online:

Residual fatigue is independent of antecedent events and disease severity in Guillain-Barré syndrome

  • M.P.J. GarssenAffiliated withDepartments of Neurology, Erasmus University Medical Center Rotterdam Email author 
  • , R. Van KoningsveldAffiliated withDepartments of Neurology, Erasmus University Medical Center Rotterdam
  • , P.A. Van DoornAffiliated withDepartments of Neurology, Erasmus University Medical Center Rotterdam

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Abstract

The occurrence of severe fatigue after Guillain-Barré syndrome (GBS), and its relation with disease course, clinical characteristics, and antecedent infections was studied in 100 GBS patients. Severe fatigue, expressed as a mean Fatigue Severity Scale (FSS) score of 5.0 or more, was present in 60% of all patients. It was more frequently present in females and in patients over 50 years (p<0.01). There was no significant relationship between fatigue severity and the level of functional disability at nadir, antecedent events or infections, clinical variables, and time to follow-up after GBS.

Keywords

Guillain-Barré syndrome fatigue disease severity antecedent events