International Journal of Legal Medicine

, Volume 114, Issue 1, pp 41–44

A Korean population study of the nine STR loci FGA, VWA, D3S1358, D18S51, D21S11, D8S1179, D7S820, D13S317 and D5S818

  • G.-R. Han
  • Y.-W. Lee
  • H.-L. Lee
  • S.-M. Kim
  • T.-W. Ku
  • I.-H. Kang
  • H.-S. Lee
  • J.-J. Hwang
Original article

DOI: 10.1007/s004140000137

Cite this article as:
Han, GR., Lee, YW., Lee, HL. et al. Int J Leg Med (2000) 114: 41. doi:10.1007/s004140000137

Abstract

DNA typing was performed on 379 randomly selected unrelated Koreans using the nine short tandem repeat loci FGA, VWA, D3S1358, D18S51, D21S11, D8S1179, D7S820, D13S317 and D5S818 present in the AmpFlSTR Profiler Plus PCR amplification kit. Allele frequencies, heterozygosity, power of discrimination, mean exclusion chance, and polymorphism information content of each locus were calculated by statistical analysis. All nine loci were in Hardy-Weinberg equilibrium. The combined discrimination index and the combined mean exclusion chance in Koreans was 2.31 × 10–12 and 0.99983, respectively. By evaluation of 297 children from 128 families, 2 mutations were found at the FGA locus and 1 each at the D18S51 and D13S317 loci. This study demonstrates that this multiplex system is a useful and convenient tool for forensic identification and parentage testing in Korea.

Key words STR Allele frequency Korea 

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • G.-R. Han
    • 1
  • Y.-W. Lee
    • 1
  • H.-L. Lee
    • 1
  • S.-M. Kim
    • 1
  • T.-W. Ku
    • 1
  • I.-H. Kang
    • 1
  • H.-S. Lee
    • 1
  • J.-J. Hwang
    • 1
  1. 1.Department of Legal Medicine, College of Medicine, Korea University, 126-1, Anam-Dong, Seongbuk-Gu, Seoul, Korea 136-705 e-mail: jjhwang@korea.ac.kr; Tel.: +82-2-9206148; Fax: +82-2-9283901KR