International Journal of Legal Medicine

, Volume 128, Issue 4, pp 599–606

Negative autopsy and sudden cardiac death

Authors

  • Oscar Campuzano
    • Cardiovascular Genetic CenterUniversity of Girona-IDIBGI
  • Catarina Allegue
    • Cardiovascular Genetic CenterUniversity of Girona-IDIBGI
  • Sara Partemi
    • Institute of Public Health, Section of Legal MedicineCatholic University
  • Anna Iglesias
    • Cardiovascular Genetic CenterUniversity of Girona-IDIBGI
  • Antonio Oliva
    • Institute of Public Health, Section of Legal MedicineCatholic University
    • Cardiovascular Genetic CenterUniversity of Girona-IDIBGI
    • Medical SchoolUniversitat de Girona
    • Cardiovascular Genetics CenterInstitut d’Investigació Biomèdica Girona-IdIBGi
Review Article

DOI: 10.1007/s00414-014-0966-4

Cite this article as:
Campuzano, O., Allegue, C., Partemi, S. et al. Int J Legal Med (2014) 128: 599. doi:10.1007/s00414-014-0966-4

Abstract

Forensic medicine defines the unexplained sudden death as a death with a non-conclusive diagnosis after autopsy. Molecular diagnosis is being progressively incorporated in forensics, mainly due to improvement in genetics. New genetic technologies may help to identify the genetic cause of death, despite clinical interpretation of genetic data remains the current challenge. The identification of an inheritable defect responsible for arrhythmogenic syndromes could help to adopt preventive measures in family members, many of them asymptomatic but at risk of sudden death. This multidisciplinary translational research requires a specialized team.

Keywords

Negative autopsySudden cardiac deathChannelopathiesGenetics

Copyright information

© Springer-Verlag Berlin Heidelberg 2014