International Journal of Legal Medicine

, Volume 125, Issue 5, pp 629–636

PopAffiliator: online calculator for individual affiliation to a major population group based on 17 autosomal short tandem repeat genotype profile

  • Luísa Pereira
  • Farida Alshamali
  • Rune Andreassen
  • Ruth Ballard
  • Wasun Chantratita
  • Nam Soo Cho
  • Clotilde Coudray
  • Jean-Michel Dugoujon
  • Marta Espinoza
  • Fabricio González-Andrade
  • Sibte Hadi
  • Uta-Dorothee Immel
  • Catalin Marian
  • Antonio Gonzalez-Martin
  • Gerhard Mertens
  • Walther Parson
  • Carlos Perone
  • Lourdes Prieto
  • Haruo Takeshita
  • Héctor Rangel Villalobos
  • Zhaoshu Zeng
  • Lev Zhivotovsky
  • Rui Camacho
  • Nuno A. Fonseca
Original Article

DOI: 10.1007/s00414-010-0472-2

Cite this article as:
Pereira, L., Alshamali, F., Andreassen, R. et al. Int J Legal Med (2011) 125: 629. doi:10.1007/s00414-010-0472-2

Abstract

Because of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to 15–17 loci. Constraints related to sample amount and quality, frequently encountered in forensic casework, will not allow to change this picture in the near future, notwithstanding the technological developments. In this study, we present a free online calculator named PopAffiliator (http://cracs.fc.up.pt/popaffiliator) for individual population affiliation in the three main population groups, Eurasian, East Asian and sub-Saharan African, based on genotype profiles for the common set of STRs used in forensics. This calculator performs affiliation based on a model constructed using machine learning techniques. The model was constructed using a data set of approximately fifteen thousand individuals collected for this work. The accuracy of individual population affiliation is approximately 86%, showing that the common set of STRs routinely used in forensics provide a considerable amount of information for population assignment, in addition to being excellent for individual identification.

Keywords

Online calculatorGenotype profileAutosomal STRsIndividual affiliation

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Luísa Pereira
    • 1
    • 2
  • Farida Alshamali
    • 3
  • Rune Andreassen
    • 4
  • Ruth Ballard
    • 5
  • Wasun Chantratita
    • 6
  • Nam Soo Cho
    • 7
  • Clotilde Coudray
    • 8
  • Jean-Michel Dugoujon
    • 8
  • Marta Espinoza
    • 9
  • Fabricio González-Andrade
    • 10
  • Sibte Hadi
    • 11
  • Uta-Dorothee Immel
    • 12
  • Catalin Marian
    • 13
  • Antonio Gonzalez-Martin
    • 14
  • Gerhard Mertens
    • 15
  • Walther Parson
    • 16
  • Carlos Perone
    • 17
  • Lourdes Prieto
    • 18
  • Haruo Takeshita
    • 19
  • Héctor Rangel Villalobos
    • 20
  • Zhaoshu Zeng
    • 21
  • Lev Zhivotovsky
    • 22
  • Rui Camacho
    • 23
    • 24
  • Nuno A. Fonseca
    • 25
  1. 1.Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP)PortoPortugal
  2. 2.Faculdade de Medicina da Universidade do PortoPortoPortugal
  3. 3.General Department of Forensic Sciences & CriminologyDubai Police GHQDubaiUAE
  4. 4.Faculty of Health SciencesOslo University CollegeOsloNorway
  5. 5.Department of Biological SciencesCalifornia State UniversitySacramentoUSA
  6. 6.Department of Pathology, Faculty of Medicine, Ramathibodi HospitalMahidol UniversityBangkokThailand
  7. 7.Department of Forensic Medicine, Central District OfficeNational Institute of Scientific InvestigationDaejeonRepublic of Korea
  8. 8.Laboratoire d’Anthropologie Moléculaire et Imagerie de Synthèse (AMIS)CNRS and University Toulouse III Paul SabatierToulouseFrance
  9. 9.Departamento de Ciencias Forenses, Organismo de Investigación Judicial, Poder JudicialUnidad de Genética ForenseSan JoséCosta Rica
  10. 10.Department of MedicineMetropolitan HospitalQuitoEcuador
  11. 11.School of Forensic & Investigative SciencesUniversity of Central LancashirePrestonUK
  12. 12.Institute of Legal MedicineMartin-Luther-University HalleHalleGermany
  13. 13.Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer CenterGeorgetown University Medical CenterWashingtonUSA
  14. 14.Department Zoology and Physical Anthropology, Faculty of BiologyUniversity Complutense of MadridMadridSpain
  15. 15.Forensic DNA LaboratoryAntwerp University HospitalEdegemBelgium
  16. 16.Institute of Legal MedicineInnsbruck Medical UniversityInnsbruckAustria
  17. 17.Núcleo de Ações e Pesquisa em Apoio Diagnóstico, Faculdade de MedicinaUniversidade Federal de Minas Gerais (NUPAD/FM-UFMG)Belo HorizonteBrazil
  18. 18.DNA Laboratory, Comisaría general de Policía CientíficaUniversity Institute of Research Police Sciences (IUICP)MadridSpain
  19. 19.Department of Legal MedicineShimane University School of MedicineIzumoJapan
  20. 20.Instituto de Investigación en Genética Molecular, Centro Universitario de la Cienega (CUCI-UdeG)Universidad de GuadalajaraOcotlánMéxico
  21. 21.Department of Legal Medicine, School of Basic Medical SciencesZhengzhou UniversityZhengzhouChina
  22. 22.Institute of General GeneticsThe Russian Academy of SciencesMoscowRussia
  23. 23.Laboratory of Artificial Intelligence and Decision Support (LIAAD-INESC)PortoPortugal
  24. 24.DEIFaculdade de Engenharia da Universidade do PortoPortoPortugal
  25. 25.CRACS-INESC Porto LAPortoPortugal