International Journal of Legal Medicine

, Volume 120, Issue 6, pp 355–359

Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims

Original Article

DOI: 10.1007/s00414-006-0105-y

Cite this article as:
Marschall, S., Rothschild, M.A. & Bohnert, M. Int J Legal Med (2006) 120: 355. doi:10.1007/s00414-006-0105-y


Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expression of Hsp70 was discernible not only particularly in the vessels but also in seromucous secretory cells, ciliated epithelial cells, smooth muscle cells, and alveolar cells. The results suggest a vital or supravital reaction due to the inhalation of hot fire fumes.


Heat-shock proteinHsp70Fire victimsAirwaysLungs

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Institute of Legal MedicineAlbert Ludwig UniversityFreiburgGermany
  2. 2.Institute of Legal MedicineUniversity of CologneCologneGermany