International Journal of Legal Medicine

, Volume 118, Issue 6, pp 364–366

MATP polymorphisms in Germans and Japanese: the L374F mutation as a population marker for Caucasoids

  • Isao Yuasa
  • Kazuo Umetsu
  • Gotaro Watanabe
  • Hiroaki Nakamura
  • Minoru Endoh
  • Yoshito Irizawa
Short Communication

DOI: 10.1007/s00414-004-0490-z

Cite this article as:
Yuasa, I., Umetsu, K., Watanabe, G. et al. Int J Legal Med (2004) 118: 364. doi:10.1007/s00414-004-0490-z

Abstract

Inference of the population and ancestry to which an individual belongs is important in forensic individualization and personal identification. In this study, five polymorphisms of the membrane-associated transporter protein (MATP) gene were investigated in German and Japanese populations. The L374F mutation was present at an allele frequency as high as 0.96 in the German population, whereas it was completely absent in the Japanese population. This extreme difference in allele frequency suggests that the L374F mutation is valuable as a population and ancestry informative marker for Caucasoids.

Keywords

Ancestry markerL374FMembrane-associated transporter proteinPolymorphismPopulation marker

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Isao Yuasa
    • 1
  • Kazuo Umetsu
    • 2
  • Gotaro Watanabe
    • 3
  • Hiroaki Nakamura
    • 4
  • Minoru Endoh
    • 1
  • Yoshito Irizawa
    • 1
  1. 1.Division of Legal Medicine Faculty of MedicineTottori UniversityYonagoJapan
  2. 2.Department of Experimental and Forensic Pathology Faculty of MedicineYamagata UniversityYamagataJapan
  3. 3.Forensic Science LaboratoryYamagata Prefectural Police HeadquartersYamagataJapan
  4. 4.Criminal Investigation LaboratoryShimane Prefectural Police HeadquartersMatsueJapan