, Volume 52, Issue 1, pp 157-159
Date: 08 Jan 2013

Comment on “Dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors” (Radiat. Environ. Biophys (2012) 51:165–178) by Schöllnberger et al.

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We read with interest the recent paper of Schöllnberger et al. (2012), which assesses the nature of the dose response for blood circulatory system diseases following exposure to ionizing radiation during the atomic bombings of Hiroshima and Nagasaki. They reach the conclusions that for cerebrovascular disease, risk estimates are compatible with no risk below a threshold dose of 0.62 Gy, while for cardiovascular disease, risk estimates are consistent with no risk below a threshold dose of 2.19 Gy. Clearly, this is pertinent to the current scientific deliberations as to whether low-level exposure to ionizing radiation increases the risk of circulatory disease.

The conclusions of a recent meta-analysis of ours of circulatory disease risk following moderate and low-dose radiation exposure (Little et al. 2012) have some bearing on the conclusions of Schöllnberger et al. (2012). The biology of radiation-associated atherosclerosis has been subject to several extensive and recent reviews (Advis ...