Investigation on circular asymmetry of geographical distribution in cancer mortality of Hiroshima atomic bomb survivors based on risk maps: analysis of spatial survival data
 Tetsuji Tonda,
 Kenichi Satoh,
 Keiko Otani,
 Yuya Sato,
 Hirofumi Maruyama,
 Hideshi Kawakami,
 Satoshi Tashiro,
 Masaharu Hoshi,
 Megu Ohtaki
 … show all 9 hide
Abstract
While there is a considerable number of studies on the relationship between the risk of disease or death and direct exposure from the atomic bomb in Hiroshima, the risk for indirect exposure caused by residual radioactivity has not yet been fully evaluated. One of the reasons is that risk assessments have utilized estimated radiation doses, but that it is difficult to estimate indirect exposure. To evaluate risks for other causes, including indirect radiation exposure, as well as direct exposure, a statistical method is described here that evaluates risk with respect to individual location at the time of atomic bomb exposure instead of radiation dose. In addition, it is also considered to split the risks into separate risks due to direct exposure and other causes using radiation dose. The proposed method is applied to a cohort study of Hiroshima atomic bomb survivors. The resultant contour map suggests that the region west to the hypocenter has a higher risk compared to other areas. This in turn suggests that there exists an impact on risk that cannot be explained by direct exposure.
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 Title
 Investigation on circular asymmetry of geographical distribution in cancer mortality of Hiroshima atomic bomb survivors based on risk maps: analysis of spatial survival data
 Open Access
 Available under Open Access This content is freely available online to anyone, anywhere at any time.
 Journal

Radiation and Environmental Biophysics
Volume 51, Issue 2 , pp 133141
 Cover Date
 20120501
 DOI
 10.1007/s0041101204024
 Print ISSN
 0301634X
 Online ISSN
 14322099
 Publisher
 SpringerVerlag
 Additional Links
 Topics
 Keywords

 Atomic bomb survivors
 Direct exposure
 Indirect exposure
 Spatial survival data
 Spatially varying coefficient
 Industry Sectors
 Authors

 Tetsuji Tonda ^{(1)}
 Kenichi Satoh ^{(1)}
 Keiko Otani ^{(1)}
 Yuya Sato ^{(2)}
 Hirofumi Maruyama ^{(3)}
 Hideshi Kawakami ^{(3)}
 Satoshi Tashiro ^{(2)} ^{(4)}
 Masaharu Hoshi ^{(5)}
 Megu Ohtaki ^{(1)}
 Author Affiliations

 1. Department of Environmetrics and Biometrics, Research Institute for Radiation Biology and Medicine, Hiroshima University, 123 Kasumi, MinamiKu, Hiroshima, 7348551, Japan
 2. Division of Radiation Information Registry, Research Institute for Radiation Biology and Medicine, Hiroshima University, 123 Kasumi, MinamiKu, Hiroshima, 7348551, Japan
 3. Department of Epidemiology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 123 Kasumi, MinamiKu, Hiroshima, 7348551, Japan
 4. Department of Cellular Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, 123 Kasumi, MinamiKu, Hiroshima, 7348551, Japan
 5. Department of Radiation Biophysics, Research Institute for Radiation Biology and Medicine, Hiroshima University, 123 Kasumi, MinamiKu, Hiroshima, 7348551, Japan