, Volume 188, Supplement 1, pp 19–22

Nitric Oxide Measurement in Chronic Cough


DOI: 10.1007/s00408-009-9187-x

Cite this article as:
Lim, K.G. Lung (2010) 188: 19. doi:10.1007/s00408-009-9187-x


Chronic cough is a common symptom-based diagnostic challenge for primary care physicians and respiratory specialists. Measurement of exhaled nitric oxide is a convenient, reproducible, and inexpensive point-of-service test. It can simplify the evaluation process of chronic cough by providing information regarding the state of airway inflammation. If exhaled nitric oxide is elevated, this is predictive of a favorable response to inhaled corticosteroids. This has the effect of reducing empirical trials for cough-variant asthma or eosinophilic bronchitis. The inclusion of exhaled nitric oxide in the diagnostic approach to chronic cough should be considered.


Chronic coughQuality of lifeExhaled nitric oxideFeNOCough-variant asthmaEosinophilic bronchitis

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of Medicine, Division of Pulmonary and Critical CareMayo Clinic RochesterRochesterUSA