, Volume 186, Supplement 1, pp 10–16

Basic Mechanisms of Cough: Current Understanding and Remaining Questions


DOI: 10.1007/s00408-007-9060-8

Cite this article as:
Lee, MG. & Undem, B.J. Lung (2008) 186: 10. doi:10.1007/s00408-007-9060-8


Considerable effort in many laboratories has gone into describing the afferent nerve subtypes that initiate cough, and the ionic mechanisms the activation and modulation of these nerves. In this brief overview, we have attempted to summarize some of what is understood in these areas. In addition, we have tried to highlight many of the important basic questions that remain to be answered.


Vagal afferent nervesNociceptorsCapsaicinBronchopulmonary C fibers

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Department of PhysiologyKorea University College of MedicineSeoulKorea
  2. 2.Asthma and Allergy CenterJohns Hopkins UniversityBaltimoreUSA