European Archives of Psychiatry and Clinical Neuroscience

, Volume 249, Issue 5, pp 256–262

A multinational study of the relationships between nighttime urinary melatonin production, age, gender, body size, and latitude

Authors

  • L. Wetterberg
    • Psychiatric Research Center University of Tromsø, PFFT at Åsgård Hospital, N-9291 Tromsø, Norway Tel.: + 47 77627 813, Fax: +47 77627 806 e-mail: Lennart.Wetterberg@rito.no
  • Trond Bratlid
    • Psychiatric Research Center University of Tromsø, PFFT at Åsgård Hospital, N-9291 Tromsø, Norway Tel.: + 47 77627 813, Fax: +47 77627 806 e-mail: Lennart.Wetterberg@rito.no
  • Lars von Knorring
    • Department of Psychiatry, University of Uppsala, Sweden
  • Göran Eberhard
    • Department of Psychiatry, University of Lund, Sweden
  • Arthur Yuwiler
    • Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, UCLA, USA
Original paper

DOI: 10.1007/s004060050095

Cite this article as:
Wetterberg, L., Bratlid, T., von Knorring, L. et al. European Archives of Psychiatry and Clinical Neurosciences (1999) 249: 256. doi:10.1007/s004060050095

Abstract

Overnight urines were collected each month for 12–16 months from 321 normal subjects at 19 medical centers in 14 countries distributed on 5 continents at latitudes from 31 01 South to 77 00 North. Mean melatonin concentration was found to negatively correlate with age, weight, and height. When the sexes were considered separately melatonin only correlated with age for female and with age and weight for males. A weak correlation with latitude, but not longitude, was also found.

Key words MelatoninUrineAgeSexHeightWeightUrine volumeLatitudeLongitude.

Copyright information

© Steinkopff Verlag 1999