European Archives of Psychiatry and Clinical Neuroscience

, Volume 263, Issue 5, pp 445–447

The serotonin 1A receptor gene in mood disorders: a tale of missed opportunities

Letter to the Editor

DOI: 10.1007/s00406-012-0381-0

Cite this article as:
Sand, P.G. Eur Arch Psychiatry Clin Neurosci (2013) 263: 445. doi:10.1007/s00406-012-0381-0


The role of the C-1019G variant in conferring susceptibility to mood disorders is an object of ongoing debate. In their recent meta-analysis of case–control investigations, Kishi and coworkers have sought to clarify the issue by pooling earlier results. Whether a claimed effect of this variant can be upheld, however, is questionable in view of numerous artefacts.


5-HT1AMood disordersAssociation

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Psychiatry and PsychotherapyUniversity of RegensburgRegensburgGermany