Letter to the Editor

European Archives of Psychiatry and Clinical Neuroscience

, Volume 263, Issue 5, pp 445-447

First online:

The serotonin 1A receptor gene in mood disorders: a tale of missed opportunities

  • Philipp G. SandAffiliated withDepartment of Psychiatry and Psychotherapy, University of Regensburg Email author 

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The role of the C-1019G variant in conferring susceptibility to mood disorders is an object of ongoing debate. In their recent meta-analysis of case–control investigations, Kishi and coworkers have sought to clarify the issue by pooling earlier results. Whether a claimed effect of this variant can be upheld, however, is questionable in view of numerous artefacts.


5-HT1A Mood disorders Association