Premenstrual symptoms and luteal suicide attempts

  • Enrique Baca-Garcia
  • Carmen Diaz-Sastre
  • Antonio Ceverino
  • Eloy García Resa
  • Maria A. Oquendo
  • Jerónimo Saiz-Ruiz
  • Jose de Leon
ORIGINAL PAPER

DOI: 10.1007/s00406-004-0506-1

Cite this article as:
Baca-Garcia, E., Diaz-Sastre, C., Ceverino, A. et al. European Archives of Psychiatry and Clinical Neurosciences (2004) 254: 326. doi:10.1007/s00406-004-0506-1

Abstract.

Objective:

If premenstrual symptoms (PMS) are temporally and specifically associated with suicidal attempts, suicide attempts in women with PMS should occur more frequently in the luteal phase.

Method:

In a general hospital, 125 fertile female suicide attempters (and 83 blood donors as controls) with regular menstrual cycles were prospectively studied. A retrospective DSM-IV diagnosis of Premenstrual Dysphoric Disorder (PMDD) was made.

Results:

Attempts during the luteal phase were not more frequent in females with PMDD (34%,23/68) than in those without PMDD (35%, 20/57). The sample had enough power to detect medium and large effect sizes. As expected, there was a significantly higher frequency of PMDD in suicide attempters than in the controls (54% vs 6%; Fisher’s exact test, p ≤ 0.001).

Conclusion:

This study was limited by the use of retrospective PMDD diagnosis but suggests that PMDD may not be associated with suicidal acts during the luteal phase,when PMS are present.

Key words

suicide attempted suicide premenstrual syndrome menstrual cycle 

Copyright information

© Steinkopff Verlag 2004

Authors and Affiliations

  • Enrique Baca-Garcia
    • 1
  • Carmen Diaz-Sastre
    • 2
  • Antonio Ceverino
    • 2
  • Eloy García Resa
    • 2
  • Maria A. Oquendo
    • 3
  • Jerónimo Saiz-Ruiz
    • 2
  • Jose de Leon
    • 4
  1. 1.Department of PsychiatryFundacion Jimenez DiazMadridSpain
  2. 2.Department of PsychiatryHospital Ramon y CajalMadridSpain
  3. 3.Conte Center for the Neurobiology of Mental Disorders, Department of NeuroscienceColumbia University and New York State Psychiatric InstituteNew YorkUSA
  4. 4.Mental Health Research Center at Eastern State HospitalLexingtonUSA

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