Reduced grey and white matter volumes in the temporal lobe of male patients with chronic schizophrenia
Purchase on Springer.com
$39.95 / €34.95 / £29.95*
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.
Magnetic resonance imaging (MRI) and tissue segmentation were used to quantify grey matter, white matter and cerebrospinal fluid (CSF) volumes in the brains of 32 males with chronic schizophrenia and 32 healthy males. Tissue volumes in the frontal, temporal, parietal, and occipital regions were measured separately. Males with schizophrenia had significant reductions of grey and white matter volumes in the temporal regions compared with controls. Patients also had significantly smaller white matter volumes in the cerebrum and increased CSF volumes in the frontal and the temporal regions as well as the cerebrum.
The findings of the present study suggest that volumes of grey and white matter are reduced in the temporal region of males with chronic schizophrenia. The volume of white matter in the whole brain also appears to be reduced. Among the different brains regions, grey matter reduction was significant only in the temporal region.
- Reduced grey and white matter volumes in the temporal lobe of male patients with chronic schizophrenia
European Archives of Psychiatry and Clinical Neuroscience
Volume 252, Issue 3 , pp 120-123
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Key words schizophrenia
- magnetic resonance imaging
- temporal lobe
- grey matter
- white matter
- cerebrospinal fluid
- Industry Sectors