European Archives of Oto-Rhino-Laryngology

, Volume 257, Issue 3, pp 117–119

Familial idiopathic facial palsy

Authors

  • F. Döner
    • Department of Otolaryngology, The Medical School, Süleyman Demirel University, TR-32040 Isparta, Turkey Tel.: +246 232 66 57-8, Fax: +246 218 01 63
  • S. Kutluhan
    • Clinic of Neurology, Kütahya State Hospital, Kütahya,Turkey
Otology

DOI: 10.1007/s004050050205

Cite this article as:
Döner, F. & Kutluhan, S. European Archives of Oto-Rhino-Laryngology (2000) 257: 117. doi:10.1007/s004050050205

Abstract

The etiology of idiopathic facial palsy (IFP) is still not defined. Familial inheritance has been found in 4–14% of cases. Among 116 patients with IFP admitted to the otolaryngology and neurology clinics at Kütahya State Hospital, 12 had positive family histories involving 10 different families. Review of the patients’ histories showed that 13 members of families previously had IFP. In all, the 25 patients with familial IFP consisted of 12 males and ¶13 females and had an average age at onset of 34.3 years. Class I human leukocyte antigen (HLA) was investigated in 11 patients with familial IFP belonging to four separate families. The follow-up period was approximately 2 months. All cases except one recovered completely, with the latter patient having minimal contracture and facial paresis. However, HLA showed no significant increases in class I antigens. No notable difference was found in the clinical courses of patients with familial and non-familial IFP.

Key words Familial idiopathic facial palsyHuman leukocyte antigen

Copyright information

© Springer-Verlag Berlin Heidelberg 2000