European Archives of Oto-Rhino-Laryngology

, Volume 269, Issue 2, pp 591–599

Evaluation of factors affecting post-treatment quality of life in oral and oropharyngeal cancer patients primarily treated with curative surgery: an exploratory study

  • Raghav C. Dwivedi
  • Suzanne St.Rose
  • Edward J. Chisholm
  • Pouya Youssefi
  • Mohammed Sultan Ul Hassan
  • Afroze S. Khan
  • Behrad Elmiyeh
  • Cyrus J. Kerawala
  • Peter M. Clarke
  • Christopher M. Nutting
  • Peter H. Rhys-Evans
  • Kevin J. Harrington
  • Rehan Kazi
Head and Neck

DOI: 10.1007/s00405-011-1621-z

Cite this article as:
Dwivedi, R.C., St.Rose, S., Chisholm, E.J. et al. Eur Arch Otorhinolaryngol (2012) 269: 591. doi:10.1007/s00405-011-1621-z

Abstract

The aim was to explore the impact of important clinico-demographic factors on the post-treatment quality of life (QOL) in surgically treated oral and oropharyngeal cancer patients. 63 consecutive follow-up oral and oropharyngeal cancer patients treated primarily with surgery were recruited. 55 patients sent the completed questionnaires and finally included in this study. QOL and important sub-domains of the QOL were assessed. Mean QOL scores (SD) were computed, level of significance was set at P < 0.05. The mean composite QOL score and standard deviation (SD) for oral and oropharyngeal cancer patients were 76.6 (15.2) and 73.4 (13.9), respectively. Patients with higher T-stage (T3 and T4) and higher overall-stage (III and IV) had lower mean QOL scores as against early T (T1 and T2) and overall early-stage (I and II); mean scores (SD) 64.3 (13.6) and 72.3 (13.8), and 76.6 (13.6) and 81.7 (14.1), respectively. Younger patients had lower mean scores (SD) than older patients; mean QOL scores (SD) 69.7 (14.0) and 79.6 (SD), respectively. Patients with reconstruction had lower mean QOL scores as compared to those without reconstruction; mean scores (SD) 67.6 (16.0) and 77.4 (12.5), respectively. In conclusion, tumor-stage, overall-stage, age of patients, and reconstruction had a significant direct effect on the post-treatment QOL of oral and oropharyngeal cancer patients.

Keywords

Quality of life (QOL) Oral cancer Oropharyngeal cancer Head and neck cancer Questionnaire UWQOL 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Raghav C. Dwivedi
    • 1
    • 2
  • Suzanne St.Rose
    • 3
  • Edward J. Chisholm
    • 1
  • Pouya Youssefi
    • 1
  • Mohammed Sultan Ul Hassan
    • 1
  • Afroze S. Khan
    • 1
  • Behrad Elmiyeh
    • 1
  • Cyrus J. Kerawala
    • 1
  • Peter M. Clarke
    • 1
  • Christopher M. Nutting
    • 1
    • 2
  • Peter H. Rhys-Evans
    • 1
    • 2
  • Kevin J. Harrington
    • 1
    • 2
  • Rehan Kazi
    • 1
    • 2
  1. 1.Head and Neck UnitRoyal Marsden HospitalLondonUK
  2. 2.The Institute of Cancer ResearchLondonUK
  3. 3.Research, Data and Statistical UnitRoyal Marsden HospitalLondonUK

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