Archives of Gynecology and Obstetrics

, Volume 288, Issue 2, pp 287–291

Pregnancy outcomes in women with mitral valve prolapse and mitral valve regurgitation

  • Tsahi T. Lerman
  • Adi Y. Weintraub
  • Eyal Sheiner
Maternal-Fetal Medicine

DOI: 10.1007/s00404-013-2755-6

Cite this article as:
Lerman, T.T., Weintraub, A.Y. & Sheiner, E. Arch Gynecol Obstet (2013) 288: 287. doi:10.1007/s00404-013-2755-6

Abstract

Purpose

To examine pregnancy and perinatal outcomes in patients with mitral valve disorders [mitral valve prolapse and/or mitral regurgitation; mitral valve disorders (MVD)].

Methods

A retrospective comparative study was conducted comparing all singleton deliveries, during the years 1988–2010, of women with and without known MVD. Women lacking prenatal care were excluded. Stratified analysis using logistic regression was performed to control for confounds.

Results

Out of 233,194 singleton deliveries that occurred during the study period, 390 deliveries occurred in women with MVD. Using a multivariate analysis, advanced maternal age (OR = 1.06; 95 % CI 1.05–1.08; P < 0.001), recurrent abortions (OR = 1.62; 95 % CI 1.15–2.28; P = 0.005), hypertensive disorders (OR = 1.62; 95 % CI 1.17–2.26; P = 0.004) and Jewish ethnicity (OR = 2.21; 95 % CI 1.76–2.79; P < 0.001) were found to be significantly associated with MVD. Since cesarean sections (CS) were significantly higher in deliveries of patients with MVD (17.9 vs. 14 %; P = 0.025), another multivariate analysis was constructed, with CS as the outcome variable. MVD was not found to be an independent risk factor for CS (OR = 1.05; 95 % CI 0.79–1.37; P = 0.74).

Conclusions

MVD associated with advanced maternal age, recurrent abortions, Jewish ethnicity and hypertensive disorders were not found to be an independent risk factor for CS.

Keywords

Mitral insufficiencyMitral incompetenceValvular diseasePerinatal outcomesCesarean sectionRecurrent pregnancy loss

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Tsahi T. Lerman
    • 1
  • Adi Y. Weintraub
    • 1
  • Eyal Sheiner
    • 1
  1. 1.Department of Obstetrics and GynecologySoroka University Medical CenterBeer-ShevaIsrael