Archives of Gynecology and Obstetrics

, Volume 286, Issue 4, pp 905–911

Prepregnancy body mass index and gestational weight gain with the outcome of pregnancy: a 13-year study of 292,568 cases in China

Maternal-Fetal Medicine

DOI: 10.1007/s00404-012-2403-6

Cite this article as:
Liu, Y., Dai, W., Dai, X. et al. Arch Gynecol Obstet (2012) 286: 905. doi:10.1007/s00404-012-2403-6

Abstract

Purpose

We aimed to investigate the combined associations of prepregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes in Chinese women.

Methods

Data for 292,568 singleton term pregnancies were selected from 1993 to 2005 based on the Perinatal Health Care Surveillance System, with anthropometric measurements being collected prospectively. Prepregnancy BMI was categorized according to the definitions of the World Health Organization (WHO). Total GWG was categorized into four groups. Adjusted associations of prepregnancy BMI and GWG with outcomes of interest were estimated using logistic regression analyses. GWG was categorized as below, within and above the Institute of Medicine (IOM) (2009) recommendations.

Results

Maternal overweight and high GWG or GWG above the IOM recommendation were associated with hypertensive disorders complicating pregnancy, cesarean delivery, macrosomia and large-for-gestational-age (LGA) infants. Maternal underweight and low GWG or GWG below the IOM recommendation were risk factors for low-birth-weight (LBW) and small-for-gestational-age (SGA) infants. Moreover, being overweight [odds ratio (OR) 1.2, 95 % confidence interval (CI) 1.0–1.3) and having a low weight gain (OR 1.1, 95 % CI 1.0–1.1) increased the risk of newborn asphyxia.

Conclusion

Being overweight/obese and having a high weight gain, as well as being underweight and having a low weight gain, were associated with increased risks for adverse pregnancy outcomes in Chinese women.

Keywords

Gestational weight gainBody mass indexPregnancyInfant

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of Epidemiology and BiostatisticsSchool of Public Health, Peking UniversityBeijingPeople’s Republic of China
  2. 2.Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive HealthPeking University Health Science CenterBeijingPeople’s Republic of China
  3. 3.Ministry of HealthBeijingChina
  4. 4.Editorial Office, Chinese Journal of OncologyCancer Hospital, Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina