Archives of Gynecology and Obstetrics

, Volume 286, Issue 3, pp 711–715

Sister Mary Joseph’s nodule associated with rare endometrial squamous cell carcinoma

  • Mohammed Tanjimur Rahman
  • Kentaro Nakayama
  • Munmun Rahman
  • Naomi Nakayama
  • Masako Ishikawa
  • Atsuko Katagiri
  • Hiroshi Katagiri
  • Tomoka Ishibashi
  • Kouji Iida
  • Kohji Miyazaki
Gynecologic Oncology

DOI: 10.1007/s00404-012-2356-9

Cite this article as:
Rahman, M.T., Nakayama, K., Rahman, M. et al. Arch Gynecol Obstet (2012) 286: 711. doi:10.1007/s00404-012-2356-9
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Abstract

Background

Umbilical metastasis (Sister Mary Joseph’s nodule) is a rare physical sign seen only in 1–3 % of patients with an intra-abdominal and/or pelvic malignancy. Here, we present a case of Sister Mary Joseph’s (SMJN) nodule originating from a primary squamous cell carcinoma of the endometrium, a rare histological subtype.

Case history

SMJN was detected in a 30-year-old woman after a preoperative CT scan for a suspected umbilical hernia. Subsequent laparotomy and histopathological examination confirmed endometrial squamous cell carcinoma metastasizing to the umbilical region.

Conclusion

The SMJN may be the first presenting sign of an intra-abdominal and/or pelvic malignancy and may co-exist with an umbilical hernia. Therefore, malignancy should be considered one of the differentials of an umbilical mass.

Keywords

Sister Mary Joseph’s noduleUmbilical herniaPrimary endometrial squamous cell carcinoma

Abbreviations

SMJN

Sister Mary Joseph’s nodule

PESCC

Primary endometrial squamous cell carcinoma

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Mohammed Tanjimur Rahman
    • 1
  • Kentaro Nakayama
    • 1
  • Munmun Rahman
    • 1
  • Naomi Nakayama
    • 2
  • Masako Ishikawa
    • 1
  • Atsuko Katagiri
    • 1
  • Hiroshi Katagiri
    • 1
  • Tomoka Ishibashi
    • 1
  • Kouji Iida
    • 1
  • Kohji Miyazaki
    • 1
  1. 1.Department of Obstetrics and GynecologyShimane University School of MedicineIzumoJapan
  2. 2.Department of BiochemistryShimane University School of MedicineIzumoJapan