Reproductive Medicine

Archives of Gynecology and Obstetrics

, Volume 286, Issue 2, pp 495-503

Use of progestogens in pregnant and infertile patients

  • Tülay ÖzlüAffiliated withDepartment of Obstetrics and Gynecology, İzzet Baysal Medical Faculty, Abant İzzet Baysal UniversitySağlık Araştırma ve Uygulama Merkezi, Abant İzzet Baysal Üniversitesi Email author 
  • , Ayşenur Çakır GüngörAffiliated withDepartment of Obstetrics and Gynecology, Faculty of Medicine, Canakkale Onsekiz Mart University
  • , Melahat Emine DönmezAffiliated withDepartment of Obstetrics and Gynecology, İzzet Baysal Medical Faculty, Abant İzzet Baysal University
  • , Bülent DuranAffiliated withDepartment of Obstetrics and Gynecology, İzzet Baysal Medical Faculty, Abant İzzet Baysal University

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Abstract

Progesterone is an essential hormone in the occurence and maintenance of pregnancy. Natural or synthetic progestogens are commonly used in pregnant patients or patients undergoing infertility treatments for various indications. Most frequently put indications for the use of progestogens in these patient populations are the prevention of spontaneous preterm birth, the prevention of pregnancy loss in pregnancies with an unexplained recurrent pregnancy loss and in patients with threatened abortion. It is also used in pregnant women undergoing nonobstetric surgery, for infertility or recurrent pregnancy loss that is thought to be due to luteal phase defect or as a luteal support in stimulated IVF cycles. We aimed to review the current evidence for the use of progestogens in each of these settings.

Keywords

Abortion Luteal phase Preterm Progesterone Progestogen Short cervix