Archives of Gynecology and Obstetrics

, Volume 286, Issue 1, pp 203–208

Detection and genotyping of cervical HPV with simultaneous cervical cytology in Turkish women: a hospital-based study

  • Kunter Yuce
  • Ahmet Pinar
  • Mehmet Coskun Salman
  • Alpaslan Alp
  • Berkan Sayal
  • Selen Dogan
  • Gulsen Hascelik
Gynecologic Oncology

DOI: 10.1007/s00404-012-2280-z

Cite this article as:
Yuce, K., Pinar, A., Salman, M.C. et al. Arch Gynecol Obstet (2012) 286: 203. doi:10.1007/s00404-012-2280-z

Abstract

Purpose

To investigate the prevalence of cervical human papilloma virus (HPV) with genotyping and simultaneous cervical cytology among Turkish women in a university hospital. A review of literature was done as well to summarize the results of similar Turkish studies based on hospital data.

Methods

Women who were subjected to cervical HPV-DNA testing with simultaneous cervical Pap test were included. Seeplex HPV 18-plex Genotyping Test was used for HPV detection and typing. Liquid-based cytology was used for Pap test and Bethesda system was used for results.

Results

Study group included 890 patients with a mean age of 39.5 years. The prevalence of any HPV was 25.7% while high-risk HPV was positive in 23.0%. There were no significant differences in HPV prevalence between younger and older women. Among HPV-positive women, 89.5% had at least one type of high-risk HPV. Most common HPV was type 16 followed by type 31 and 51. Abnormal cervical cytology rate was 11.6%. Rate of HPV positivity was significantly higher in women with abnormal cervical cytology compared to women with normal cytology (54.4 vs. 22.0%).

Conclusions

Cervical HPV infection is a serious and gradually growing problem for Turkish women according to hospital-based data. This may be associated with low age at marriage and more sensitive HPV detection methods.

Keywords

Cervical cancerHuman papilloma virusPap smearTurkey

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Kunter Yuce
    • 1
  • Ahmet Pinar
    • 2
  • Mehmet Coskun Salman
    • 1
  • Alpaslan Alp
    • 2
  • Berkan Sayal
    • 1
  • Selen Dogan
    • 1
  • Gulsen Hascelik
    • 2
  1. 1.Department of Obstetrics and Gynecology, Faculty of MedicineHacettepe UniversityAnkaraTurkey
  2. 2.Department of Medical Microbiology, Faculty of MedicineHacettepe UniversityAnkaraTurkey