Date: 25 Feb 2012
Laparoscopic and laparotomic approaches for endometrial cancer treatment: a comprehensive review
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Endometrial cancer (EC) is the most common gynecological malignancy in the developed world, particularly among postmenopausal women. Endoscopic surgery is gaining more popularity among surgeons as a safe and feasible option for treatment of endometrial carcinoma, providing the possibility of adequate lymph node excision.
A comprehensive review.
The advantages of laparoscopy prevail over laparotomy and authors report lower peri-operative complication rates, less blood loss, lower transfusion rates, and shorter hospital stay, as well as a better quality of life (QoL) after laparoscopic surgery, in contrast to conventional abdominal surgery. This was confirmed by a meta-analysis of four randomized controlled studies. This is also true for obese risky patients to whom laparotomies carry indolent side effects. In addition, with more training and experience this procedure would be even more feasible and safer.
Because of the increasing importance of economic efficiency in health care, the endoscopic approach will continue to play a more important role in the future treatment of EC providing a better treatment option for the coming patients. As a promising therapeutical option, it should be offered to all patients with an early-stage EC.
Ingolf Juhasz-Böss and Hisham Haggag contributed equally.
AGO, DKG, DGGG Diagnostik und Therapie des Endometriumkarzinoms. Interdisziplinäre S2-Leitlinie, AWMF 032/034
National Collaborating Centre for Women’s and Children’s Health (2007) Heavy menstrual bleeding. RCOG Press, London [http://www.nice.org.uk/nicemedia/pdf/CG44FullGuideline.pdf]
Breijer MC, Timmermans A, van Doorn HC, Mol BW, Opmeer BC (2010) Diagnostic strategies for postmenopausal bleeding. Obstet Gynecol Int 2010:850812PubMed
Gao WL, Zhang LP, Feng LM (2011) Comparative study of transvaginal ultrasonographic and diagnostic hysteroscopic findings in postmenopausal breast cancer patients treated with tamoxifen. Chin Med J (Engl) 124(15):2335–2339
Alcazar JL, Galvan R (2009) Three-dimensional power Doppler ultrasound scanning for the prediction of endometrial cancer in women with postmenopausal bleeding and thickened endometrium. Am J Obstet Gynecol 200(1):44.e1–44.e6CrossRef
Petric A, Stojanov D, Lilic V, Filipovic S, Bosnjakovic P, Zivadinovic R, Lilic G, Todorovska I, Vrbic S, Pejcic I (2011) The application of magnetic resonance imaging in preoperative evaluation of patients with endometrial carcinoma. J BUON 16(3):492–497PubMed
Boruta DM 2nd, Growdon WB, McCann CK, Garrett LA, Del Carmen MG, Goodman A, Schorge JO (2011) Evolution of surgical management of early-stage endometrial cancer. Am J Obstet Gynecol 205(6):565.e1–565.e6CrossRef
Solomayer EF, Becker S (2007) Neue Entwicklungen der Zervixkarzinom-Chirurgie-der laparoskopische Wertheim. Geburtshilfe Frauenheilkd 12:1375–1377CrossRef
Magrina JF, Weaver AL (2004) Laparoscopic treatment of endometrial cancer: five-year recurrence and survival rates. Eur J Gynaecol Oncol 25:439–441PubMed
Zullo F, Palomba S, Russo T, Falbo A, Costantino M, Tolino A, Zupi E, Tagliaferri P, Venuta S (2005) A prospective randomized comparison between laparoscopic and laparotomic approaches in women with early stage endometrial cancer: a focus on the quality of life. Am J Obstet Gynecol 193(4):1344–1352PubMedCrossRef
Holub Z, Voracek J, Shomani A (1998) A comparison of laparoscopic surgery with open procedure in endometrial cancer. Eur J Gynaecol Oncol 19(3):294–296PubMed
Hidlebaugh DA, Orr RK (1997) Staging endometrioid adenocarcinoma. Clinical and financial comparison of laparoscopic and traditional approaches. J Reprod Med 42:482–488PubMed
Holub Z, Jabor A, Bartos P, Eim J, Urbánek S, Pivovarniková R (2002) Laparoscopic surgery for endometrial cancer: long-term results of a multicentric study. Eur J Gynaecol Oncol 23(4):305–310PubMed
Ostrzenski A (1999) Laparoscopic total abdominal hysterectomy in morbidly obese women. A pilot-phase report. J Reprod Med 44:853–858PubMed
- Laparoscopic and laparotomic approaches for endometrial cancer treatment: a comprehensive review
Archives of Gynecology and Obstetrics
Volume 286, Issue 1 , pp 167-172
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Endometrial cancer
- Peri-operative complication
- Oncological safety
- Industry Sectors
- Author Affiliations
- 1. Department of Obstetrics and Gynecology, University of Saarland, Kirrbergerstr. 100, 66424, Homburg, Saar, Germany
- 2. Department of Obstetrics and Gynecology, Kasr AlAini Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt