Archives of Gynecology and Obstetrics

, Volume 284, Issue 6, pp 1473–1479

Relationship between endometriosis and cancer from current perspective

Gynecologic Oncology

DOI: 10.1007/s00404-011-2047-y

Cite this article as:
Kokcu, A. Arch Gynecol Obstet (2011) 284: 1473. doi:10.1007/s00404-011-2047-y

Abstract

Purpose

To examine the current mechanisms of the increased incidence of cancer in women with endometriosis.

Methods

The synthesis and review of the relevant current literature in English language.

Results

Compared with general population, women with endometriosis have two times higher risk for developing ovarian cancer, 30% higher risk for developing breast cancer, and 40% higher risk for developing hematopoietic malignancies, mainly non-Hodgkin lymphoma.

Conclusions

Endometriosis comprises many predisposing factors including genetic, epigenetic, local environmental, hormonal, inflammatory and immunologic changes, for the development of some cancers.

Keywords

Endometriosis Cancer Genetic Epigenetic Hormone 

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  1. 1.Department of Obstetrics and Gynecology, School of MedicineUniversity of Ondokuz MayisSamsunTurkey
  2. 2.Bahcelievler mah, Abdülhakhamid CadSamsunTurkey